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Rangaramanujam M Kannan Selected Research

Dendrimers (Dendrons)

1/2022Systemic administration of dendrimer N-acetyl cysteine improves outcomes and survival following cardiac arrest.
1/2022Dendrimer-Based N-Acetyl Cysteine Maternal Therapy Ameliorates Placental Inflammation via Maintenance of M1/M2 Macrophage Recruitment.
10/2021Systemic dendrimer nanotherapies for targeted suppression of choroidal inflammation and neovascularization in age-related macular degeneration.
10/2021Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma.
10/2021Systemic dendrimer delivery of triptolide to tumor-associated macrophages improves anti-tumor efficacy and reduces systemic toxicity in glioblastoma.
5/2021Targeted systemic dendrimer delivery of CSF-1R inhibitor to tumor-associated macrophages improves outcomes in orthotopic glioblastoma.
2/2021Dendrimer-Triamcinolone Acetonide Reduces Neuroinflammation, Pathological Angiogenesis, and Neuroretinal Dysfunction in Ischemic Retinopathy.
1/2021Dendrimer-tesaglitazar conjugate induces a phenotype shift of microglia and enhances β-amyloid phagocytosis.
12/2020Dendrimer-Mediated Targeted Delivery of Rapamycin to Tumor-Associated Macrophages Improves Systemic Treatment of Glioblastoma.
10/2020Systemic dendrimer-drug nanomedicines for long-term treatment of mild-moderate cerebral palsy in a rabbit model.
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Rangaramanujam M Kannan Research Topics

Disease

25Neuroinflammatory Diseases
01/2022 - 12/2008
16Inflammation (Inflammations)
01/2022 - 11/2010
12Brain Injuries (Brain Injury)
10/2020 - 04/2012
10Neoplasms (Cancer)
12/2021 - 03/2013
10Cerebral Palsy (Spastic Diplegia)
10/2020 - 04/2009
7Glioblastoma (Glioblastoma Multiforme)
12/2021 - 06/2015
7Brain Neoplasms (Brain Tumor)
12/2021 - 06/2015
6Infections
05/2014 - 06/2010
4Disease Progression
10/2021 - 10/2020
4Macular Degeneration (Age-Related Maculopathy)
10/2021 - 01/2012
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 01/2020
3Premature Birth (Birth, Premature)
01/2022 - 08/2014
3Retinal Diseases
02/2021 - 03/2015
3Ischemia
02/2021 - 07/2015
3Retinal Degeneration
01/2021 - 01/2012
3Rett Syndrome (Rett's Disorder)
01/2020 - 12/2017
3Chorioamnionitis
10/2016 - 02/2010
2Diabetic Retinopathy (Retinopathy, Diabetic)
02/2021 - 07/2015
2Poisoning
01/2021 - 07/2018
2Necrosis
01/2021 - 09/2016
2Glioma (Gliomas)
12/2020 - 05/2020
2Dry Eye Syndromes (Dry Eye Syndrome)
10/2018 - 01/2017
2Nervous System Diseases (Neurological Disorders)
07/2018 - 11/2017
2Stroke (Strokes)
04/2009 - 12/2008
2Carcinoma (Carcinomatosis)
02/2006 - 01/2004
1Heart Arrest (Cardiac Arrest)
01/2022
1Muscle Weakness
01/2022
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2022
1Asphyxia (Suffocation)
01/2022
1Residual Neoplasm
12/2021
1Cardiotoxicity
10/2021
1COVID-19
10/2021
1Choroidal Neovascularization
10/2021
1Glaucoma
02/2021
1Pathologic Neovascularization
02/2021
1Cataract (Cataracts)
02/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2021
1Non-alcoholic Fatty Liver Disease
01/2021
1Coma (Comas)
10/2020
1Traumatic Brain Injuries (Traumatic Brain Injury)
10/2020
1Cognitive Dysfunction
12/2018
1Dacryocystitis (Dacryoadenitis)
10/2018
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018

Drug/Important Bio-Agent (IBA)

51Dendrimers (Dendrons)IBA
01/2022 - 01/2004
27Pharmaceutical PreparationsIBA
01/2022 - 01/2004
15Hydroxyl RadicalIBA
10/2021 - 01/2012
11Poly(amidoamine)IBA
10/2021 - 11/2010
8Cysteine (L-Cysteine)FDA Link
01/2022 - 04/2009
8LigandsIBA
10/2021 - 11/2010
8PAMAM StarburstIBA
10/2020 - 03/2006
6Acetylcysteine (Siran)FDA LinkGeneric
01/2022 - 12/2008
5Retinaldehyde (Retinal)IBA
10/2021 - 01/2012
3CytokinesIBA
10/2021 - 01/2017
3Anti-Bacterial Agents (Antibiotics)IBA
05/2014 - 06/2011
2Mannose (D-Mannose)IBA
10/2021 - 10/2018
2HydrogelsIBA
01/2021 - 08/2011
2Acetaminophen (Paracetamol)FDA LinkGeneric
01/2021 - 07/2018
2AntioxidantsIBA
10/2020 - 12/2008
2Dexamethasone (Maxidex)FDA LinkGeneric
10/2018 - 01/2017
2Coloring Agents (Dyes)IBA
07/2015 - 12/2013
2Anti-Inflammatory Agents (Anti-Inflammatories)IBA
04/2009 - 12/2008
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2021
1Scavenger Receptors (Scavenger Receptor)IBA
12/2021
1deoxythymidylyl-3'-5'-deoxyadenylate (d(T-A))IBA
10/2021
1SugarsIBA
10/2021
1Galactose (Galactopyranose)FDA LinkGeneric
10/2021
1Glucose (Dextrose)FDA LinkGeneric
10/2021
1Galectins (Galectin)IBA
10/2021
1triptolideIBA
10/2021
1Macrophage Colony-Stimulating FactorIBA
05/2021
14- (2- (2- hydroxycyclohexylamino)benzothiazol- 6- yloxy)pyridine- 2- carboxylic acid methylamideIBA
05/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
02/2021
1Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
02/2021
1GemcitabineFDA Link
01/2021
1IntegrinsIBA
01/2021
1Paclitaxel (Taxol)FDA LinkGeneric
01/2021
1Liposomes (Liposome)IBA
01/2021
1tesaglitazarIBA
01/2021
1Proteins (Proteins, Gene)FDA Link
01/2021
1Lipid PeroxidesIBA
01/2021
1LipidsIBA
01/2021
1Sirolimus (Rapamycin)FDA Link
12/2020
1sinomenineIBA
10/2020
1Biological ProductsIBA
01/2020
1Glutamic Acid (Glutamate)FDA Link
01/2020
1GlutaminaseIBA
01/2020
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
01/2020
1Toll-Like Receptors (Toll-Like Receptor)IBA
12/2018
1LipopolysaccharidesIBA
12/2018
1AntidotesIBA
07/2018
1monooctanoin (Moctanin)FDA Link
07/2018

Therapy/Procedure

25Therapeutics
01/2022 - 11/2010
4Drug Therapy (Chemotherapy)
10/2018 - 08/2011
3Injections
12/2021 - 08/2011
2Immunotherapy
05/2021 - 12/2020
2Intravenous Administration
07/2018 - 10/2017
1Denervation
01/2022
1Intravenous Injections
12/2021
1Induced Hypothermia
10/2020